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Clonorchiasis: treatment with praziquantel in 50 cases.

Kuang Qh, Zhou Yt, Lei Sz, Cao Wj, Zhong Hl

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Abstract

Of 50 patients infected with Clonorchis sinensis, 3 groups were formed and treated with different doses of praziquantel (2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a] isoquinolin- 4-one). 24 patients out of 50 were followed up for 3 months and another 10 for 6 months. It is evident that this single-day treatment is effective and satisfactory. In 5 patients with glucose-6-phosphate dehydrogenase deficiency no haemolysis occurred.

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What this paper is about

Of 50 patients infected with Clonorchis sinensis, 3 groups were formed and treated with different doses of praziquantel (2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a] isoquinolin- 4-one). 24 patients out of 50 were followed up for 3 months and another 10 for 6 months. It is evident that this single-day treatment is effective and satisfactory. In 5 patients with glucose-6-phosphate dehydrogenase deficiency no haemolysis occurred.

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Available abstract

Of 50 patients infected with Clonorchis sinensis, 3 groups were formed and treated with different doses of praziquantel (2-cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a] isoquinolin- 4-one). 24 patients out of 50 were followed up for 3 months and another 10 for 6 months. It is evident that this single-day treatment is effective and satisfactory. In 5 patients with glucose-6-phosphate dehydrogenase deficiency no haemolysis occurred.

Key concepts: Clonorchiasis, Praziquantel, Clonorchis sinensis, Gastroenterology, Medicine, Paragonimiasis, Internal medicine, Helminthiasis

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