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Thalamic Deep Brain Stimulation for Parkinson's Disease Tremor

Daniel Tarsy, Efstathios Papavassiliou, Kelly E. Lyons, Rajesh Pahwa

Abstract

Thalamic deep brain stimulation (DBS) was introduced for the treatment of Parkinson's disease (PD) tremor and essential tremor (ET) in the late 1980s. Its remarkable success for these indications was followed by the introduction of DBS in other brain targets for the treatment of PD and dystonia. With the advent of subthalamic DBS for PD, the use of thalamic DBS for PD tremor has markedly declined. However, thalamic DBS is effective for PD tremor and remains a valid option in selected older patients with tremor predominant PD who do not have other disabling features of PD.

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Available abstract

Key concepts: Deep brain stimulation, Thalamic stimulator, Essential tremor, Dystonia, Parkinson's disease, Medicine, Subthalamic nucleus, Neuroscience