2015•Applied Radiation and IsotopesOpen access

Synthesis optimization of 2-(4-N-[11C]methylaminophenyl)-6-hydroxybenzothiazole ([11C]PIB), β-amyloid PET imaging tracer for Alzheimer's disease diagnosis

Angela Coliva, Cristina Monterisi, A Apollaro, Domenico L. Gatti, Michele Penso, Luigi Gianolli, Daniela Perani, Maria Carla Gilardi, Assunta Carpinelli

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Key concepts: Radiosynthesis, Chemistry, Pet imaging, Positron emission tomography, High-performance liquid chromatography, Radiochemistry, TRACER, Nuclear chemistry

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Synthesis optimization of 2-(4-N-[11C]methylaminophenyl)-6-hydroxybenzothiazole ([11C]PIB), β-amyloid PET imaging tracer for Alzheimer's disease diagnosis — Research Paper | ScholarLens