Molybdenum Cofactor-Containing Oxidoreductase Family in Plants
Pavel Sauer, Ivo Frébort
Abstract
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Pavel Sauer, Ivo Frébort
Abstract
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Recent investigations on plant molybdenum-containing enzymes that include xanthine dehydrogenase (EC 1.1.1.204) and xanthine oxidase (EC 1.1.3.22), nitrate reductase (EC 1.7.1.1-3), aldehyde oxidase (EC 1.2.3.1), and sulfite oxidase (EC 1.8.3.1) are reviewed. The enzymes belong to closely related protein family and share common structural features. Special attention is being paid to the recently solved crystal structures their implications for the substrate binding and catalytic mechanism.
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Recent investigations on plant molybdenum-containing enzymes that include xanthine dehydrogenase (EC 1.1.1.204) and xanthine oxidase (EC 1.1.3.22), nitrate reductase (EC 1.7.1.1-3), aldehyde oxidase (EC 1.2.3.1), and sulfite oxidase (EC 1.8.3.1) are reviewed. The enzymes belong to closely related protein family and share common structural features. Special attention is being paid to the recently solved crystal structures their implications for the substrate binding and catalytic mechanism.
Key concepts: Sulfite oxidase, Aldehyde oxidase, Molybdenum cofactor, Xanthine dehydrogenase, Xanthine oxidase, Oxidoreductase, Molybdenum, Nitrate reductase