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[Comparative evaluation of sucralfate (Venter) and cimetidine (Altramet) efficiency in treatment of chronic erosive gastritis].

Zbigniew Kula, J Rudziński, L Walasek

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Abstract

The results of patients with chronic erosive gastritis treated with sucralfate (Venter) and cimetidine (Altramet) were compared. 50 patients were treated with 4.0 g of sucralfate daily and 42 patients with 1000 mg of cimetidine daily. After 4 weeks of treatment endoscopic assessment of 13 patients (26.0%) treated with sucralfate and 5 patients (11.6%) treated with cimetidine was normal. It was possible to heal only the erosions of 33 (66.0%) and 17 (40.5%) patients respectively, while the mucosal elevations remained. The result of examinations indicate, that chronic erosive gastritis is difficult to be healed; sucralfate proved to be more efficient than cimetidine.

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What this paper is about

The results of patients with chronic erosive gastritis treated with sucralfate (Venter) and cimetidine (Altramet) were compared. 50 patients were treated with 4.0 g of sucralfate daily and 42 patients with 1000 mg of cimetidine daily. After 4 weeks of treatment endoscopic assessment of 13 patients (26.0%) treated with sucralfate and 5 patients (11.6%) treated with cimetidine was normal. It was possible to heal only the erosions of 33 (66.0%) and 17 (40.5%) patients respectively, while the mucosal elevations remained. The result of examinations indicate, that chronic erosive gastritis is difficult to be healed; sucralfate proved to be more efficient than cimetidine.

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Available abstract

The results of patients with chronic erosive gastritis treated with sucralfate (Venter) and cimetidine (Altramet) were compared. 50 patients were treated with 4.0 g of sucralfate daily and 42 patients with 1000 mg of cimetidine daily. After 4 weeks of treatment endoscopic assessment of 13 patients (26.0%) treated with sucralfate and 5 patients (11.6%) treated with cimetidine was normal. It was possible to heal only the erosions of 33 (66.0%) and 17 (40.5%) patients respectively, while the mucosal elevations remained. The result of examinations indicate, that chronic erosive gastritis is difficult to be healed; sucralfate proved to be more efficient than cimetidine.

Key concepts: Sucralfate, Cimetidine, Medicine, Gastroenterology, Gastritis, Internal medicine, Chronic gastritis, Stomach

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[Comparative evaluation of sucralfate (Venter) and cimetidine (Altramet) efficiency in treatment of chronic erosive gastritis]. — Research Paper | ScholarLens